SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb35c2ec9e8ac1d622eed0e7d308ac328e41baed0bb1cbcf943d8b3489807213' 
  AND token = 'THLpvgw4QhGoJgmSt4fuy0IOi4ApSPiZjPVFFySRTLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}