SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59ca37c18a443a24cd9142fca13d1038861175f6bb27118c6ff2e8257d69d99' 
  AND token = 'HzV33VUP4YtfUT255lc09On1eu0dYyR+pF4lkqsAnFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}