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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5054a38a099c6b6f61e2fd0a74bca6016b449318ba963bc2a66d019abf7e0f2e' 
  AND token = 'zkXuWg7tW8iz89/FAlN8HwK5PJGIANkR+ogMZOL6Kt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}