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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f08c60b68a9652bed4a185a512d026fcf5ceec40c7851d75bd1f2151c1b1f8' 
  AND token = '0OFwIGOs1xLIKX0nr7NHBrCkCbRGUGPnkyHDGSrukPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}