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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3adb6da7d034115b6a3c04dead0bca037a280bc79b19fb77a1863bdbb45cfd1f' 
  AND token = 'QsR9OY2BasH0Yqx2gqze7jxyZ5YzzouaYR0VW/Fhj/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}