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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225e189b5289fd7a6becdc19bf4024f866adb38ea6c8c8cdd817d89c8e9e6285' 
  AND token = 'M0jMlKnVJJ1rzOMg3PjoelCuZ5/4Llxd9EBYaFBM/bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}