SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e4696d9872306f1a1f7c32346abd22d43e87e14e8eade37084818a806a200a' 
  AND token = 'RwFb0hB6tZtxoN/ejXRW2wZcYZeN31FErqZwbYnH1Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}