SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a7a15accb350f9db25b52a13fa9d10fd9b51f9ed23eba8ba8ef7a6de111150' 
  AND token = 'mM0+xmvIlB47vy0lD1Hw/MPfDkA0YHMy6w1Qx1lXNrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}