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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e889d107ac1b391b774843f6ea998cd56b16e405442c0d683c2131d62b4ee257' 
  AND token = '9+5UByZIVLGQ26JZDoNMoTZu9axvWfQzIAg0WpoeZiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}