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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645f1ef1adfac91cebd9d471dc0946e2dba0b5922309dfa96c5c3fa17fd99b95' 
  AND token = '4KKrQNhAUsbL67U+hJmW9rgl/4GH5v1k+A5F5hE6WJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}