SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980780f29a797b1ae367ab86fff0b88d59cebef59d465cd241fc6c8bcd97ebef' 
  AND token = 'XaPvkDw3+35WNVGJwLsiQtkzXSYrxKbzjy0MjXK5ULk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}