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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a73525a7945423260b8870338a8831504901279935f81854a84574d47e8fe02' 
  AND token = '+5dCDzDEOyv0TVy3sZd62y3hQya8KK3bN4PfgwbB/hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}