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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b9ef5440258c73c2f79d1726b9171c5a205bf302564e2b7ed8e27cca06e7e3' 
  AND token = 'wE/6DVNKUxuzYkoyLtqEz1mvyl+7x/1kUxudgq97vYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}