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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5844c0a0876b84fd8359f7155fc30db4b563d951bf5720d8a59dd4f31b546369' 
  AND token = 'IJft1AuWkOGcQADqT0OdKpIQnM1AjIR7drAYb4XmBls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}