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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a139a8230f30ee9427781e8f29d50a36e72f0c6874182d6e1fa2c03ac44c1cf' 
  AND token = 'yrppaWQqIjZ0O0C6sWXC957VhS27OsAcaIvJe+0UWf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}