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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4eb40727da9c884a9fe1221199ff7b017e3db42544f2e942dc2fa3da9d8be9c' 
  AND token = 'xnyseL6fFLSBNBZB/eezBqAnDSu+EWR+5x0yisStrvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}