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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e22b3d22ec734dea0b12ecf17f8a97ddbfc0daa3d2012a48e81e9eeadac1e59' 
  AND token = 'jvOFpiJyy+Ui1Gb2TxTpngddBk6iG1K4Mjgm0DOfwko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}