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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c8013a6791dab58063f1a76d38ad7d0bc8702e25d674e72bd3b75bd9eb7a2e' 
  AND token = '+CE9pyMiNKLMefM+UgtaDoNDNQXrhkdb5kziJg3fDhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}