SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '685cb93b5e2677cb1ad22d8f1d4c41733845bf81b177708abc0331490e761f60' 
  AND token = 'vDEJM3To1iyJe2lBsRIFDSG/CIBVYQpDm4Nxzpvb0SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}