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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5b2d7c5236c1a10f142f25e4e2506b5ea701a8eb81a51e1761a4e51a976867' 
  AND token = 'F11Ak4pKAHrjRsvU/wX043NWhBS5YxNgScZPKeAey/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}