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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8dcb90025bb0b36e8946e14297584d4b408f272dead1f55cf4671ce475a376' 
  AND token = '/GR3AAp84aLbq2LZQmqzuzlxcO1Ycq/9YrhaPXyo2uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}