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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768431b8f12b04e7779c1f7ff8177f4231f6c641bb11685b8e39d23a158dabbf' 
  AND token = 'UFMvqtw9NnrHxMM065lsRxJ1bb8T38D0vOpD4GZDuPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}