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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05d8766e2b101b7bb33db6aaad64c40861fe16fd9f8e2ff3da7858c8bdd5a905' 
  AND token = 'JTz8Pk3wlbxqX3zXwm+DhZDf2HHa6SLiLNsLZ4RaMfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}