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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d4f477d30cb9103f427c7fa73be6bbd94005a1653a01c6ab1a0355e29f2e03' 
  AND token = '3fBN1EZo1wg5w74tKjA8TxQI8PkhWH0Wm0fo7GV4LZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}