SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b769aa7b0283fd1baf371205990afa2f461c9e25290c5cfbba12c1dcec8e0149' 
  AND token = '0yjoSB74Lhk62PW1ByQyq1uCqwwYsX3LUDXpXJLJs5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}