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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73c34e3f0db74d5b09b6ea4fa93aa72429a1c7f8dac817e92d2fecc0bbc3896' 
  AND token = 'IsuhL2X5HiWHIM6CUsnJBYj7+W2eDt6Ojx5dkxGb/Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}