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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c86d6d4bad65a70c739c0a9b12111e3f5acf7d2821363ed5bf8b714baa01b59' 
  AND token = '2ph9H0lR9aViK/6kBp4L4WscyWAWGfYKr3JZ2yhs9+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}