SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649764edfad9fae1b97d297995d536548023b6a489df3e684b743f8fb227988d' 
  AND token = 'O1TrrbaHa1BCNbcStG9Dgc0cIR4n3mn9me0xXhbWjXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}