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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e8796e35b6fc38fd0fb67bf4931910721a5f00092aa58cfb1f1a42e22f485c' 
  AND token = 'escvW3YwlFNuv3muOp/fmdMMij/awG6nIcOmXZuNOGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}