SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7efe2436a2aeba4709b9363fd1075bb8bc6256ea65bc7937096d84641fc59b6' 
  AND token = 'TnJj6dqZss7t5YVs27P4tpV9rtzPQ8LfMFo7nAbOM1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}