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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa2b53b461c6bd92b31bc3aaf51897e297cc39679a668ac98146ab4181c6424c' 
  AND token = 'HFzk/TafBZrNs2Y75DwDiHliqis14ozj0nhVDdShpJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}