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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ece382db1bdaa39112a906c535d2b65eef9891183acf2a4db2bd08106e3f0e' 
  AND token = 'Zzkz6yuOI/OvgbzXBIpoDz2ZyI7co3KXJtYa1WrKKsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}