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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e294c12cd7b1120256d3a1055fa460b8b417a69c15a3555a1f2e3ea33217c41' 
  AND token = 'VT4DF2et7dQVMqVWai62Xcb5SHcCmNs4snoaTLIUmtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}