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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3429a823f5428788d9c1242866067c4156038c9ae1df0fbfac747e5393b76be0' 
  AND token = 'tfs+K3JsZdcZ7Ztc9sKfOVgo/labSAFpDNtPhOzW6IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}