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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805c4fa3381f7fc8935f56ac764ae6e8a27698d5d227ed1093e922ceb04b8609' 
  AND token = 'HSI+Ey3BxJeGemZDwIOXhQ6IeZ0y3znWrbtDqMTtoa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}