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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4a43ba7693ec4509e1a1b05542854f218f5feff7b15056a5b7d46d08594c62a' 
  AND token = 'StpUJ6lMN9+ZCb0a1uYAyPnQbsltAgPZ1WBqvMLdSKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}