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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ae61b06e385d50618951d19534892051c04400679975b517709b5c1e07a451' 
  AND token = '4ZFysNRAKMiLiL+Lf4TOc/0Y0r/1+YtX5MIBtNbafpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}