SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322857a185d5008901bd74f3f2aa68ff6cca518fca68c3d275866a123f94bc5e' 
  AND token = 'Ve912iHM6/sIwUDq18bzSwO+nKwHTKfmUI3q0Egu3Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}