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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7debc19bcaa55909c7c6c922f732cb58b5781c82f3d7b137fb6ce8471479110' 
  AND token = 'EunD3+9CV6FXoZvoKDlcZg8EE/YbZg1G6nkEQnYZCnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}