SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7b76194c83ec036aadbaa24f62067a25d4f838ba1bd57cd10154901b841294' 
  AND token = 'gjbrrfAO4s+v8FT0wbykWTwUf3V6RV8C6RadL926tSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}