SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d51a393ee40c07709dd828ed8eed8b73e208810fcaa0f13081aab31b82865d' 
  AND token = 'CuE2jcWNbXXBoSjrUDJqPcKT12O4MZFlCW9YmMhn8eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}