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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d467c7173e9396837a7e6d8094bee160921ed32bd89eb0ad09414e8fedcb43' 
  AND token = 'vH8PxUKyOEAA0wsdE/dGNG08N2YTEg1q+PRSRfQg7fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}