SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1cdfa28abf2d86a03e3ea5d34762cdf097de9f09a2ff08a797e3ccfad32c14' 
  AND token = 'Fwlqi/AkKnGfWKJwhGjEP265zgZ+H1M7mK+cQPtDXuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}