SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cff1bf120802b586a11cb004638d65e286fbd13c920d5e4d627264a47ee84d7a' 
  AND token = 'KV5brJcnRj5j6Cd+pvXrsoOjuXOv2RW+gd0N61Njt8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}