SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00293c5a10d3c0bfeb4077a4983b2993d58777741b7dca6a814f940f82f46022' 
  AND token = 't0I2MR+sdSinEpOO45Q76WJYV8fdB5fnNb25mf1Y07A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}