SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ce5356fb186c3a68bd5832ec81e6ab5917dafd8688a07f18d71ee009b78179d' 
  AND token = 'I6Cj25rFuwEbIHnUH8kL3FyAeeP5JYiEyDRaJ5MRFcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}