SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595d6925f2cc377e1fdd87e74342507ea5a3f9b19a811bf8676befeaa2714f89' 
  AND token = 'aunKDOa1KMAyl+QiNI9+wnc1pnZNg4WyBxNN+2ax1Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}