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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b8482d6a26b6863f72b1d92a091ae8f8a8a26da11f26dedf55d7097a47786c' 
  AND token = 'uo+NWj9NgWMCM1iSF9kzYoSyDpUF0nW6tlpEFwacNT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}