SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6961abe57c64fba396cf91afc8984964d0bdc3a8eab59ebe9439d32798ad70f' 
  AND token = 'cs/M25EG4O9eA9ckUujPn8yKZ+M3qSzyAqHgAxU2Nx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}