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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b859556f69e0c84b13356401c72c4d66d2c2d07ab7dbe886de2d51ecdb39e8' 
  AND token = 'oVX8/qbUpD/mUZ58B13B5XCbdeGQPh7uunihSOoYOvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}